![]() “It’s important to understand how it works so we can potentially develop even better drugs to treat type 2 diabetes.” “Metformin is the most commonly used drug to treat diabetes,” says Shulman. Cowgill Professor of Medicine (Endocrinology) and professor of cellular and molecular physiology, and first author Traci LaMoia, a graduate student in Shulman’s lab, published their findings in PNAS on March 1. ![]() The team, including senior author Gerald Shulman, MD, PhD, George R. ![]() Now, Yale researchers have elucidated the mechanism behind metformin and related type 2 diabetes drugs, and debunked a previously held theory on how they work. Physicians have used the drug metformin to treat type 2 diabetes for more than half a century, but despite its prevalence, researchers have lacked a clear understanding of how it works. ![]()
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